Syllabus:

Practical exercises:

• Experiment to demonstrate sympathomimmetic effects etc. qualitatively in experimental animals.

• Experiment to demonstrate certain actions in experimental animals which are characteristic of antipsychotic compounds.

• Experiment to identify the unknown drug based on the blood pressure recording of anaesthetized animal.

• Analysis of the data.

• Discussion of the given scientific paper.

• Critical views of the given prescription.

• Presentation of the dissertation work.

• Demonstration of the concept of competitive antagonism by using appropriate tissue and drugs.

• Estimating the potency of ACH solution by using appropriate biological tissue.

• Presenting a short lecture on the given topic.

• Preparing a protocol for the clinical trial of the new drug.

Theory:

• PHARMACOKINETICS AND PHARMACODYNAMICS: THE DYNAMICS OF DRUG ABSORPTION, DISTRIBUTION, ACTION, AND ELIMINATION MEMBRANE TRANSPORTERS AND DRUG RESPONSE DRUG METABOLISM PHARMACOGENETICS
• THE SCIENCE OF DRUG THERAPY
• NEUROTRANSMISSION: THE AUTONOMIC AND SOMATIC MOTOR NERVOUS SYSTEMS
• MUSCARINIC RECEPTOR AGONISTS AND ANTAGONISTS
• ANTICHOLINESTERASE AGENTS
• AGENTS ACTING AT THE NEUROMUSCULAR JUNCTION AND AUTONOMIC GANGLIA
• ADRENERGIC AGONISTS AND ANTAGONISTS
• 5-HYDROXYTRYPTAMINE (SEROTONIN): RECEPTOR AGONISTS AND ANTAGONISTS
• NEUROTRANSMISSION AND THE CENTRAL NERVOUS SYSTEM
• GENERAL ANESTHETICS
• LOCAL ANESTHETICS
• THERAPEUTIC GASES: OXYGEN, CARBON DIOXIDE, NITRIC OXIDE, AND HELIUM
• HYPNOTICS AND SEDATIVES
• DRUG THERAPY OF DEPRESSION AND ANXIETY DISORDERS
• PHARMACOTHERAPY OF PSYCHOSIS AND MANIA
• PHARMACOTHERAPY OF THE EPILEPSIES
• TREATMENT OF CENTRAL NERVOUS SYSTEM DEGENERATIVE DISORDERS
• OPIOID ANALGESICS
• ETHANOL
• DRUG ADDICTION AND DRUG ABUSE
• HISTAMINE, BRADYKININ, AND THEIR ANTAGONISTS
• LIPID-DERIVED AUTACOIDS: EICOSANOIDS AND PLATELET-ACTIVATING FACTOR
• ANALGESIC-ANTIPYRETIC AGENTS; PHARMACOTHERAPY OF GOUT
• PHARMACOTHERAPY OF ASTHMA
• DIURETICS
• VASOPRESSIN AND OTHER AGENTS AFFECTING THE RENAL CONSERVATION OF WATER
• RENIN AND ANGIOTENSIN
• TREATMENT OF MYOCARDIAL ISCHEMIA
• THERAPY OF HYPERTENSION
• PHARMACOTHERAPY OF CONGESTIVE HEART FAILURE
• ANTIARRHYTHMIC DRUGS
• DRUG THERAPY FOR HYPERCHOLESTEROLEMIA AND DYSLIPIDEMIA
• PHARMACOTHERAPY OF GASTRIC ACIDITY, PEPTIC ULCERS, AND GASTROESOPHAGEAL REFLUX DISEASE
• TREATMENT OF DISORDERS OF BOWEL MOTILITY AND WATER FLUX; ANTIEMETICS; AGENTS USED IN BILIARY AND PANCREATIC DISEASE
• PHARMACOTHERAPY OF INFLAMMATORY BOWEL DISEASE
• CHEMOTHERAPY OF PROTOZOAL INFECTIONS: MALARIA
• CHEMOTHERAPY OF PROTOZOAL INFECTIONS: AMEBIASIS, GIARDIASIS, TRICHOMONIASIS, TRYPANOSOMIASIS, LEISHMANIASIS, AND OTHER PROTOZOAL INFECTIONS
• CHEMOTHERAPY OF HELMINTH INFECTIONS
• GENERAL PRINCIPLES OF ANTIMICROBIAL THERAPY
• SULFONAMIDES, TRIMETHOPRIM-SULFAMETHOXAZOLE, QUINOLONES, AND AGENTS FOR URINARY TRACT INFECTIONS
• PENICILLINS, CEPHALOSPORINS, AND OTHER b-LACTAM ANTIBIOTICS
• AMINOGLYCOSIDES
• PROTEIN SYNTHESIS INHIBITORS AND MISCELLANEOUS ANTIBACTERIAL AGENTS
• CHEMOTHERAPY OF TUBERCULOSIS, MYCOBACTERIUM AVIUM COMPLEX DISEASE, AND LEPROSY
• ANTIMICROBIAL AGENTS: ANTIFUNGAL AGENTS
• ANTIVIRAL AGENTS (NONRETROVIRAL)
• ANTIRETROVIRAL AGENTS AND TREATMENT OF HIV INFECTION
• ANTINEOPLASTIC AGENTS
• IMMUNOSUPPRESSANTS, TOLEROGENS, AND IMMUNOSTIMULANTS
• HEMATOPOIETIC AGENTS: GROWTH FACTORS, MINERALS, AND VITAMINS
• BLOOD COAGULATION AND ANTICOAGULANT, THROMBOLYTIC, AND ANTIPLATELET DRUGS
• PITUITARY HORMONES AND THEIR HYPOTHALAMIC RELEASING HORMONES
• THYROID AND ANTITHYROID DRUGS
• ESTROGENS AND PROGESTINS
• ANDROGENS
• ADRENOCORTICOTROPIC HORMONE; ADRENOCORTICAL STEROIDS AND THEIR SYNTHETIC ANALOGS; INHIBITORS OF THE SYNTHESIS AND ACTIONS OF ADRENOCORTICAL HORMONES
• INSULIN, ORAL HYPOGLYCEMIC AGENTS, AND THE PHARMACOLOGY OF THE ENDOCRINE PANCREAS
• AGENTS AFFECTING MINERAL ION HOMEOSTASIS AND BONE TURNOVER
• DERMATOLOGICAL PHARMACOLOGY
• OCULAR PHARMACOLOGY
• PRINCIPLES OF TOXICOLOGY AND TREATMENT OF POISONIN
• HEAVY METALS AND HEAVY-METAL ANTAGONISTS

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